Gestational diabetes mellitus (GDM) is a critical condition affecting maternal and fetal health, requiring timely screening and effective management. Screening typically involves oral glucose tolerance tests during the second trimester to identify impaired glucose tolerance. Management strategies focus on individualized lifestyle interventions, including medical nutrition therapy, physical activity, and weight management, complemented by pharmacotherapy such as insulin or oral hypoglycemic agents when needed. Continuous blood glucose monitoring ensures optimal glycemic control, reducing the risk of complications such as macrosomia, preeclampsia, and neonatal hypoglycemia. Multidisciplinary care involving obstetricians, endocrinologists, dietitians, and diabetes educators is essential for effective management. By implementing evidence-based screening and personalized treatment approaches, healthcare providers can improve maternal outcomes and support healthy fetal development.