Diabetic neuropathy is a common and debilitating complication of diabetes, characterized by nerve damage that can lead to pain, sensory loss, and impaired mobility. Advances in therapy focus on both symptom management and disease modification. Pharmacological treatments include anticonvulsants, antidepressants, and topical agents that alleviate neuropathic pain. Lifestyle interventions, such as glycemic control, physical activity, and dietary optimization, play a key role in preventing progression. Emerging strategies, including neuromodulation techniques, regenerative therapies, and novel pharmacological agents targeting oxidative stress and inflammation, are expanding treatment options. By integrating conventional and innovative approaches, healthcare providers can improve patient outcomes, reduce neuropathic complications, and enhance quality of life for individuals living with diabetic neuropathy.